{"id":1942,"date":"2024-04-22T22:31:56","date_gmt":"2024-04-23T02:31:56","guid":{"rendered":"https:\/\/9bio.ca\/?p=1942"},"modified":"2026-01-20T09:25:24","modified_gmt":"2026-01-20T14:25:24","slug":"9bio-is-awarded-a-grant-from-the-national-research-council-canada-nrc-irap","status":"publish","type":"post","link":"https:\/\/9biotx.com\/fr\/news\/9bio-is-awarded-a-grant-from-the-national-research-council-canada-nrc-irap\/","title":{"rendered":"9Bio re\u00e7oit une subvention du Conseil national de recherches Canada (CNRC-PARI)"},"content":{"rendered":"<p><strong>Qu\u00e9bec, le 22 avril 2024<\/strong> \u2013 9Bio Th\u00e9rapeutiques, une entreprise biotechnologique sp\u00e9cialis\u00e9e dans le d\u00e9veloppement de th\u00e9rapies oncologiques de nouvelle g\u00e9n\u00e9ration, est heureuse d\u2019annoncer qu\u2019elle recevra un financement de 75 000 $ du Programme d\u2019aide \u00e0 la recherche industrielle du Conseil national de recherches Canada (CNRC-PARI) pour soutenir le d\u00e9veloppement de son programme principal \u2013 un conjugu\u00e9 anticorps-m\u00e9dicament (ADC) de pr\u00e9cision.<\/p>\n\n\n\n<p>Cet ADC a \u00e9t\u00e9 con\u00e7u pour cibler les tumeurs tout en \u00e9pargnant les tissus sains et s\u2019attaquera aux cancers de la vessie et du foie envahissants les muscles \u2013 des cancers pr\u00e9sentant des besoins m\u00e9dicaux non combl\u00e9s importants. Ce projet permettra de valider l\u2019ing\u00e9nierie <em>in silico<\/em>de 9Bio en traduisant ses mod\u00e8les computationnels en applications exp\u00e9rimentales en laboratoire, afin de confirmer la sp\u00e9cificit\u00e9 tumorale.<\/p>\n\n\n\n<p style=\"font-size:26px\"><strong>Exploiter la biologie structurale guid\u00e9e par l\u2019IA pour les ADC de nouvelle g\u00e9n\u00e9ration<\/strong><\/p>\n\n\n\n<p>L\u2019approche de 9Bio int\u00e8gre les derni\u00e8res avanc\u00e9es en biologie structurale assist\u00e9e par l\u2019intelligence artificielle avec l\u2019ing\u00e9nierie computationnelle des prot\u00e9ines afin de concevoir des th\u00e9rapies anticanc\u00e9reuses hautement s\u00e9lectives. Contrairement aux ADC conventionnels, qui peuvent entra\u00eener une toxicit\u00e9 importante pour les tissus sains, notre plateforme se concentre sur la limitation de l\u2019activit\u00e9 th\u00e9rapeutique aux tumeurs, r\u00e9duisant ainsi l\u2019exposition syst\u00e9mique, am\u00e9liorant la s\u00e9curit\u00e9 et augmentant l\u2019efficacit\u00e9.<\/p>\n\n\n\n<p>\u00ab Gr\u00e2ce au soutien du CNRC-PARI, nous acc\u00e9l\u00e9rons le d\u00e9veloppement d\u2019une th\u00e9rapie oncologique de pr\u00e9cision de premier ordre \u00bb, a d\u00e9clar\u00e9 Philipe Gobeil, Pr\u00e9sident et Directeur scientifique de 9Bio<strong>.<\/strong><em> <\/em>\u00ab En exploitant la mod\u00e9lisation structurale guid\u00e9e par l\u2019IA, nous pouvons optimiser le ciblage tumoral, garantissant que notre ADC se lie s\u00e9lectivement uniquement l\u00e0 o\u00f9 il est n\u00e9cessaire, minimisant la toxicit\u00e9 et maximisant le potentiel th\u00e9rapeutique. \u00bb<\/p>\n\n\n\n<p>9Bio remercie le CNRC-PARI pour son soutien<strong>.<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>\u00c0 propos de 9Bio Th\u00e9rapeutiques<\/strong><\/p>\n\n\n\n<p>9Bio est une entreprise de biotechnologie d\u00e9di\u00e9e au d\u00e9veloppement de th\u00e9rapies oncologiques innovantes. Notre plateforme de biologie structurale guid\u00e9e par l'IA int\u00e8gre des contextes anatomiques et biochimiques pour concevoir des m\u00e9dicaments ciblant s\u00e9lectivement les tumeurs. Gr\u00e2ce \u00e0 cette approche, nous d\u00e9veloppons des traitements sp\u00e9cifiquement dirig\u00e9s contre les tumeurs, tout en pr\u00e9servant les tissus sains, am\u00e9liorant ainsi la s\u00e9curit\u00e9, l\u2019efficacit\u00e9 et ouvrant la voie \u00e0 des modalit\u00e9s th\u00e9rapeutiques jusqu\u2019ici sous-exploit\u00e9es. Notre pipeline comprend deux th\u00e9rapies en phase de d\u00e9couverte : un conjugu\u00e9 anticorps-m\u00e9dicament (ADC) ciblant les cellules tumorales chimior\u00e9sistantes et un autre ADC ciblant les cellules immunitaires subverties par les tumeurs.<\/p>","protected":false},"excerpt":{"rendered":"<p>9Bio Th\u00e9rapeutiques est heureuse d\u2019annoncer qu\u2019elle recevra un financement de 75 000 $ du Programme d\u2019aide \u00e0 la recherche industrielle du Conseil national de recherches Canada (CNRC-PARI) pour soutenir le d\u00e9veloppement de son programme principal \u2013 un conjugu\u00e9 anticorps-m\u00e9dicament (ADC) de pr\u00e9cision.<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-1942","post","type-post","status-publish","format-standard","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - 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